Berberine Breakthrough

Name: Berberine Breakthrough
Brand: BIOptimizers
Price: 59.0 USD
Availability: InStock

$59.00

$59.00 $51.00

Advanced formula that supports healthy glucose levels already within the normal range and healthy carbohydrate metabolism.

Main Benefits:

Supports healthy insulin sensitivity
Supports blood sugar levels already within the normal range
Supports healthy appetite balance
Supports sustained energy
Supports healthy metabolism

In - stock and ready to ship

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Product details

Berberine Breakthrough is a natural supplement designed to support healthy glucose metabolism and promote blood sugar levels already within the normal range. Its advanced formula helps the body use glucose more efficiently, directing it toward the muscles instead of storing it as fat.

With every capsule, you get support for your blood sugar levels as well as support for reducing cravings, improving your energy, and promoting a more active metabolism.

Available in a 60 vegetable capsule size, this formula is a complete, safe option for those looking to care for their metabolic health naturally.

Benefits

Supports Healthy Blood Sugar Levels Already Within the Normal Range. Helps maintain glucose levels within the normal range, especially useful for those who frequently eat simple carbohydrates.
Supports Insulin Sensitivity. Supports a more efficient response to insulin, helping the body better process the sugars you eat.
Supports Carbohydrate Metabolism. Helps the body use carbohydrates as an energy source instead of storing them as fat.
Supports Fewer Cravings. By helping stabilize glucose levels, it may help ease sudden hunger spikes and cravings.
Supports Energy Levels. A more efficient metabolism translates into greater vitality and daily performance.

Key ingredients

Berberine Breakthrough stands out as a plant-based, advanced formula that:

Naturally supports pancreas and digestive system function
Supports metabolic balance as part of a gentle approach
May complement lifestyle changes like better nutrition and exercise

Certifications and Quality

Made in the USA
Domestic and imported ingredients
100% plant-based and free of common allergens
Version 2.0 formula

How to use

Recommended dose: 2 capsules before each meal

Storage: Keep in a cool, dry place

Caution

Keep out of reach of children. Stop use if you experience adverse effects. Talk to your doctor before starting if you're under medical care or following a specific diet.

Scientific studies

References cited by BIOptimizers, the manufacturer of this product, on its official page. They are included for reference and do not replace the guidance of a health professional.

Wang C, Wang Y, Ma SR, et al. Berberine inhibits adipocyte differentiation, proliferation and adiposity through down-regulating galectin-3. Sci Rep. 2019;9(1):13415. Published 2019 Sep 16. doi:10.1038/s41598-019-50103-5 View study
Karsono AH, Tandrasasmita OM, Tjandrawinata RR. Bioactive fraction from Lagerstroemia speciosa leaves (DLBS3733) reduces fat droplet by inhibiting adipogenesis and lipogenesis. J Exp Pharmacol. 2019;11:39-51. Published 2019 May 2. doi:10.2147/JEP.S181642 View study
Lee SG, Siaw JA, Kang HW. Stimulatory Effects of Cinnamon Extract (Cinnamomum cassia) during the Initiation Stage of 3T3-L1 Adipocyte Differentiation. Foods. 2016;5(4):83. Published 2016 Dec 6. doi:10.3390/foods5040083 View study
Zakerkish M, Jenabi M, Zaeemzadeh N, Hemmati AA, Neisi N. The Effect of Iranian Propolis on Glucose Metabolism, Lipid Profile, Resistance, Renal Function and Inflammatory Biomarkers in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind Clinical Trial. Sci Rep. 2019 May 13;9(1):7289. doi: 10.1038/s41598-019-43838-8. PMID: 31086222; PMCID: PMC6514000. View study
Alam MA, Uddin R, Subhan N, Rahman MM, Jain P, Reza HM. Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome. J Lipids. 2015;2015:496169. doi:10.1155/2015/496169 View study
Kim J, Yang G, Kim Y, Kim J, Ha J. AMPK activators: mechanisms of action and physiological activities. Exp Mol Med. 2016;48(4):e224. Published 2016 Apr 1. doi:10.1038/emm.2016.16 View study
Raichle ME, Gusnard DA. Appraising the brain's energy budget. Proc Natl Acad Sci U S A. 2002;99(16):10237-10239. doi:10.1073/pnas.172399499 View study
Ríos JL, Francini F, Schinella GR. Natural Products for the Treatment of Type 2 Diabetes Mellitus. Planta Med. 2015;81(12-13):975-994. doi:10.1055/s-0035-1546131 View study
Wang CW, Su SC, Huang SF, et al. An Essential Role of cAMP Response Element Binding Protein in Ginsenoside Rg1-Mediated Inhibition of Na+/Glucose Cotransporter 1 Gene Expression.Mol Pharmacol. 2015;88(6):1072-1083. doi:10.1124/mol.114.097352 View study
Hui H, Tang G, Go VL. Hypoglycemic herbs and their action mechanisms. Chin Med. 2009;4:11. Published 2009 Jun 12. doi:10.1186/1749-8546-4-11 View study
Hlebowicz J, Hlebowicz A, Lindstedt S, et al. Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, glucose-dependent polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects. Am J Clin Nutr. 2009;89(3):815-821. doi:10.3945/ajcn.2008.26807 View study
Gao S, Guo Q, Qin C, Shang R, Zhang Z. Sea Buckthorn Fruit Oil Extract Alleviates Resistance through the PI3K/Akt Signaling Pathway in Type 2 Diabetes Mellitus Cells and Rats. J Agric Food Chem. 2017;65(7):1328-1336. doi:10.1021/acs.jafc.6b04682 View study
Zhao J, Zhou H, An Y, Shen K, Yu L. Biological effects of corosolic acid as an anti-inflammatory, anti-metabolic syndrome and anti-neoplasic natural compound. Oncol Lett. 2021;21(2):84. doi:10.3892/ol.2020.12345 View study
Sheng X, Zhang Y, Gong Z, Huang C, Zang YQ. Improved Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors. PPAR Res. 2008;2008:581348. doi:10.1155/2008/581348 View study
Pershadsingh HA. Alpha-lipoic acid: physiologic mechanisms and indications for the treatment of metabolic syndrome. Expert Opin Investig Drugs. 2007;16(3):291-302. doi:10.1517/13543784.16.3.291 View study
Chao CY, Huang CJ. Bitter gourd (Momordica charantia) extract activates peroxisome proliferator-activated receptors and upregulates the expression of the acyl CoA oxidase gene in H4IIEC3 hepatoma cells. J Biomed Sci. 2003;10(6 Pt 2):782-791. doi:10.1159/000073966 View study
Beekmann K, Rubió L, de Haan LH, et al. The effect of quercetin and kaempferol aglycones and glucuronides on peroxisome proliferator-activated receptor-gamma (PPAR-γ). Food Funct. 2015;6(4):1098-1107. doi:10.1039/c5fo00076a View study
Maeda H. Nutraceutical effects of fucoxanthin for obesity and diabetes therapy: a review. J Oleo Sci. 2015;64(2):125-132. doi:10.5650/jos.ess14226 View study

Source: BIOptimizers official page. Only the scientific references cited by the manufacturer are shown (18).

Supplements are not intended to diagnose, treat, cure, or prevent any disease.

Part of these systems

Metabolic Health