Cognibiotics
Product description
Advanced probiotics for the mind and digestive system with adaptogenic herbs for emotional balance and mental clarity.
Main Benefits:
- Supports mood and emotional balance
- Supports mental clarity and a calm mind
- Supports gut health
- Supports concentration and memory
- Supports the gut-brain axis
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Product details
Key ingredients
How to use
Scientific studies
References cited by BIOptimizers, the manufacturer of this product, on its official page. They are included for reference and do not replace the guidance of a health professional.
- Yu M, Jia HM, Zhang T, et al. Gut Microbiota is the Key to the Antidepressant Effect of Chaihu-Shu-Gan-San. Metabolites. 2020;10(2):63. Published 2020 Feb 10. doi:10.3390/metabo10020063 View study
- Morais, L. H., Schreiber, H. L., 4th, & Mazmanian, S. K. (2020). The gut microbiota-brain axis in behaviour and brain disorders. Nature reviews. Microbiology, 10.1038/s41579-020-00460-0. Advance online publication. https://doi.org/10.1038/s41579-020-00460-0 View study
- Cryan JF, O'Riordan KJ, Cowan CSM, et al. The Microbiota-Gut-Brain Axis. Physiol Rev. 2019;99(4):1877-2013. doi:10.1152/physrev.00018.2018 View study
- Howes MR, Fang R, Houghton PJ. Effect of Chinese Herbal Medicine on Alzheimer's Disease. Int Rev Neurobiol. 2017;135:29-56. doi:10.1016/bs.irn.2017.02.003 View study
- Wang H, Lee IS, Braun C, Enck P. Effect of Probiotics on Central Nervous System Functions in Animals and Humans: A Systematic Review. Neurogastroenterol Motil. 2016;22(4):589-605. doi:10.5056/jnm16018 View study
- Dehhaghi M, Kazemi Shariat Panahi H, Guillemin GJ. Microorganisms, Tryptophan Metabolism, and Kynurenine Pathway: A Complex Interconnected Loop Influencing Human Health Status. Int J Tryptophan Res. 2019;12:1178646919852996. Published 2019 Jun 19. doi:10.1177/1178646919852996 View study
- Ohland CL, Kish L, Bell H, et al. Effects of Lactobacillus helveticus on murine behavior are dependent on diet and genotype and correlate with alterations in the gut microbiome. Psychoneuroendocrinology. 2013;38(9):1738-1747. doi:10.1016/j.psyneuen.2013.02.008 View study
- Feng DD, Tang T, Lin XP, et al. Nine traditional Chinese herbal formulas for the treatment of depression: an ethnopharmacology, phytochemistry, and pharmacology review. Neuropsychiatr Dis Treat. 2016;12:2387-2402. Published 2016 Sep 20. doi:10.2147/NDT.S114560 View study
- Qiu J, Hu SY, Shi GQ, Wang SE. Changes in regional cerebral blood flow with Chaihu-Shugan-San in the treatment of major depression. Pharmacogn Mag. 2014;10(40):503-508. doi:10.4103/0973-1296.141775 View study
- Fukuda S, Nojima J, Motoki Y, et al. A potential biomarker for fatigue: Oxidative stress and anti-oxidative activity. Biol Psychol. 2016;118:88-93. doi:10.1016/j.biopsycho.2016.05.005 View study
- Schönfeld P, Wojtczak L. Short- and medium-chain fatty acids in energy metabolism: the cellular perspective. J Lipid Res. 2016;57(6):943-954. doi:10.1194/jlr.R067629 View study
- Chambers ES, Preston T, Frost G, Morrison DJ. Role of Gut Microbiota-Generated Short-Chain Fatty Acids in Metabolic and Cardiovascular Health. Curr Nutr Rep. 2018;7(4):198-206. doi:10.1007/s13668-018-0248-8 View study
- Braniste V, Al-Asmakh M, Kowal C, et al. The gut microbiota influences blood-brain barrier permeability in mice [published correction appears in Sci Transl Med. 2014 Dec 10;6(266):266er7. Guan, Ng Lai [corrected to Ng, Lai Guan]]. Sci Transl Med. 2014;6(263):263ra158. doi:10.1126/scitranslmed.3009759 View study
- Puddu A, Sanguineti R, Montecucco F, Viviani GL. Evidence for the gut microbiota short-chain fatty acids as key pathophysiological molecules improving diabetes. Mediators Inflamm. 2014;2014:162021. doi:10.1155/2014/162021 View study
- Limbana T, Khan F, Eskander N. Gut Microbiome and Depression: How Microbes Affect the Way We Think. Cureus. 2020;12(8):e9966. Published 2020 Aug 23. doi:10.7759/cureus.9966 View study
- Allen J, Romay-Tallon R, Brymer KJ, Caruncho HJ, Kalynchuk LE. Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression. Front Neurosci. 2018;12:386. Published 2018 Jun 6. doi:10.3389/fnins.2018.00386 View study
- Keller J, Gomez R, Williams G, et al. HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition. Mol Psychiatry. 2017;22(4):527-536. doi:10.1038/mp.2016.120 View study
- Raison CL, Miller AH. Is depression an inflammatory disorder? Curr Psychiatry Rep. 2011;13(6):467-475. doi:10.1007/s11920-011-0232-0 View study
- Calarge CA, Devaraj S, Shulman RJ. Gut permeability and depressive symptom severity in unmedicated adolescents. J Affect Disord. 2019;246:586-594. doi:10.1016/j.jad.2018.12.077 View study
- Walker WH 2nd, Walton JC, DeVries AC, Nelson RJ. Circadian rhythm disruption and mental health. Transl Psychiatry. 2020;10(1):28. Published 2020 Jan 23. doi:10.1038/s41398-020-0694-0 View study
- Shalev H, Serlin Y, Friedman A. Breaching the blood-brain barrier as a gate to psychiatric disorder. Cardiovasc Psychiatry Neurol. 2009;2009:278531. doi:10.1155/2009/278531 View study
- Rao TS, Asha MR, Ramesh BN, Rao KS. Understanding nutrition, depression and mental illnesses. Indian J Psychiatry. 2008;50(2):77-82. doi:10.4103/0019-5545.42391 View study
Source: BIOptimizers official page. Only the scientific references cited by the manufacturer are shown (22).
Supplements are not intended to diagnose, treat, cure, or prevent any disease.
Part of these systems
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Cognibiotics
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